-localization of drug effects at subcellular resolution-
We developed Molecular Tattoo, a novel tool in optopharmacology.
It enables localization of drug effects at subcellular resolution in live biological objects including whole animals. Molecular Tattoo combines photoaffinity-labeling with two-photon microscopy. Precise sequential laser irradiation is used to covalently enrich low concentration photoreactive drugs on their specific targets. This results in a strong and permanent drug effect that is restricted solely to the irradiated area.
- precise and permanent effect localization
- no systemic and side effects outside the target area
- scaling of the targeted area: from organs or cell groups down to subfemtoliter volumes
- the usual in vitro and in vivo samples can be used without genetic modification.
For more information, please go to moleculartattoo.com