Offered molecules

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Non-phototoxic, stable and non-cytotoxic myosin inhibitor, para-nitroblebbistatin

paranitroblebbistatin

Reference: Para-nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitor by M. Képiró, B. H. Várkuti, L. Végner, G. Vörös, Gy. Hegyi, M. Varga, A. Málnási-Csizmadia in Angewandte Chemie Volume 53, Issue 31, July 28, 2014, DOI: 10.1002/anie.201403540 Pubmed link

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Photoreactive myosin inhibitor, azidoblebbistatin

azidoblebbistatin

Reference: Azidoblebbistatin, a photoreactive myosin inhibitor by Miklós Képiró, Boglárka H. Várkuti, Andrea Bodor, György Hegyi, László Drahos, Mihály Kovács, András Málnási-Csizmadia in Proc Natl Acad Sci U S A. 2012 Jun 12; 109(24):9402-7. doi: 10.1073/pnas.1202786109 Pubmed link

In vivo application reference: Molecular tattoo: subcellular confinement of drug effects by Képiró M, Várkuti BH, Rauscher AA, Kellermayer MS, Varga M, Málnási-Csizmadia A. in Chem Biol. 2015 Apr 23;22(4):548-58. doi: 10.1016/j.chembiol.2015.03.013 Pubmed link

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Highly soluble derivative, para-aminoblebbistatin

para NH_blebbistatin_file1_greyReference: A highly soluble, non-phototoxic, non-fluorescent blebbistatin derivative by Boglárka H. Várkuti; Miklós Képiró;  Ádám I. Horváth; László Végner; Szilvia Ráti; Áron Zsigmond; György Hegyi; Zsolt Lenkei; Máté Varga  in  Scientific Reports. 6: 26141. 2016 May 31 doi:10.1038/srep26141 PubMed Link

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